Interstate Highway No. 380 links Cedar Falls and neighboring Waterloo with the southeastern area of the State and connects with Interstate Highway No. 80.
Cedar Falls is accessible by U.S. Highways No. 20, 63, and 218. Highways 218 and 20 are part of Interstate 27, which is also known as the Avenue of the Saints.
Cedar Falls is also accessible by State Highways No. 21, 57, 281, and 412.
Interstate Highway No. 35 is located about 65 miles west of the City.